Folcker was born as Jessica Elisabeth Angelique Folcker in Täby, a Stockholm suburb, on July 9, 1975. Her mother is Swedish and father is from Senegal.

Jessica attended a music school for six years until she was 17. Her big dream of becoming a singer, was fulfilled when she was engaged as a backing singer for the Ace of Base and Dr. Alban. She also performed the chorus in Leila K's hit "Electric" and done background vocals for E-type.

In 1994 Jessica was selected to represent Stockholm in the Miss Sweden competition.

On Jessica's debut album, named simply Jessica and released in the autumn 1998, she worked with composer and producer Max Martin, known for having written Britney Spears' Baby One More Time. The album was an instant hit, and Jessica became an international star over night. As a result, Jessica travelled to Asia for a six week long promotional tour across Japan, the Philippines, South Korea, Taiwan and Thailand, resulting in high sales in the region, including selling gold. In South Korea, her remake of David Foster classic Goodbye was used as the theme ballad for the movie A Promise, and rapidly became the most frequently played song on South Korean radio.

In Sweden, Jessica peaked the top of the single charts with two singles from the album; How Will I Know Who You Are and Tell Me What You like, both selling platinum. She also won two prizes at the awards show of Sweden's major pop radio station, NRJ: New Artist of the Year as well as Swedish Female Artist of the Year. No artist before her had won more than one award until then.

In 2000, two years after releasing her debut album, Jessica Folcker's second album came out, called Dino, nicknamed after one of her producers. Besides Europe and Asia, Jessica wanted to conquer the USA as well this time around. However, since many Americans pronounced her surname similar to "fucker", she decided to change her name to Folker instead, without the c. Jessica's first single from the album, To Be Able To Love, became a minor hit in the states thanks to a remix by DJ Jonathan Peters, and soon Jessica went on a club tour to New York and New Jersey.

Another of Jessica Folcker's songs - Lost Without Your Love - once again became the theme tune of another Korean film, Indian Summer. Again, Jessica reached the top of the South Korean airplay chart. In April 2001, Jessica's song Miracles was chosen as the theme melody for the Dutch Fame Academy replica, Starmaker. Due to this, she decided to release the song as her second single from the album, her sixth in total.

Jessica debuted in the Swedish national selection for the Eurovision Song Contest in 2005. In Melodifestivalen 2005, she performed Om natten. 2006 she tried again, participating in the third semi final heat of Melodifestivalen 2006 on March 4 with the song When Love's Comin' Back Again. She failed, however, to qualify for the semi final.

Jessica worked in the studio on her 4th album since 2006. After being at several labels she is now signed to the Indie Label Cosmos Records. The album was released in 2007 under the title Skin Close and had an Electronic/80's Pop-sound. It was her first English-record since 2000. The only song of the record that was released as a single was Snowflakes. Due the fact of minimal promotion, Skin Close failed to make an impact on the public.